Now the top-selling female artist in the world, Yayoi Kusama overcame impossible odds to bring her radical artistic vision to the world stage. For decades, her work pushed boundaries that often alienated her from both her peers and those in power in the art world. Kusama was an underdog with everything stacked against her: the trauma of growing up in Japan during World War II, life in a dysfunctional family that discouraged her creative ambitions, sexism and racism in the art establishment, mental illness in a culture where that was particularly shameful and even continuing to pursue and be devoted to her art full time on the cusp of her 90s.